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Next-Generation Sequencing (NGS) is a new DNA sequencing technology that has completely changed the way genomic research is done by allowing researchers to study biological systems at a new level, cheaper and faster than previous methods. With NGS came the ability...
Potency testing is a term used to describe the process of measuring biological activity in a product. Many methods exist to determine the potency of a biopharmaceutical such as ligand and receptor binding assays, cell culture-based assays, and animal-based assays....
Genotyping is a process used to obtain DNA information, specifically used to determine the genetic variants or differences an individual has. Common genotyping methods include restriction fragment length polymorphism identification of genomic DNA, polymerase chain...
Histology is the study of microscopic tissues and their structures. Histology is an important part of biology, medicine and other sciences. Preparing histology samples for observation under a microscope is a delicate process using specialized techniques that are...
Pharmacogenetics is the study of how genetic differences affect a person's response to medicine. Pharmacogenetics is often used interchangeably with pharmacogenomics. Pharmacogenetic research and testing determine a person's ability to metabolize medicines and...
What is Polymerase Chain Reaction Testing? PCR stands for Polymerase Chain Reaction and may be called "molecular photocopying," as it's a technique used to "amplify," or copy, DNA segments. According to the National Institutes of Health's National Human Genome...
Biomarkers, also called biological markers, are measurable indicators of a biological condition. The exact definition is "a characteristic that is objectively measured and evaluated as an indicator of normal biological processes, pathogenic processes or...
What is CCIT? Container Closure Integrity Testing (CCIT) is done to evaluate the strength and integrity of a container closure system. Testing of container closures is important as it ensures a sterile barrier against microorganisms and other potentially dangerous...
With the overuse of antibiotics, antimicrobial resistance testing has been in the news a great deal. Contract Laboratory frequently works with pharmaceutical and healthcare companies on their antimicrobial resistance testing. Antimicrobials are agents used to kill...
Methicillin-resistant Staphylococcus aureus (MRSA) is a Staph Bacteria Recently, ContractLaboratory.com received a request from a company seeking a microbiology laboratory or surface testing for pathogenic bacteria & viruses including MRSA, which stands for...
According to the NIH, during clinical trials, more than 60 percent of investigational drugs fail, even if they showed promising results in pre-clinical studies on cell and animal research. To stop this from happening, NIH has announced it will award 13 "Tissue Chip...
By now it is standard knowledge that chemicals in cigarettes and other tobacco containing products are dangerous. Due to their dangerous nature, the FDA requires tobacco producers to report the levels of Harmful or Potentially Harmful Constituents (HPHCs) in their...
The drug development process is an iterative process. Each stage of development helps to ensure the final product is effective and safe. Preclinical drug development, often called preclinical studies, is the stage in the drug development process where the safety of...
According to a new study based on data obtained from forty-seven countries performed by the US Center for Disease Control (CDC) and other global health agencies, estimates of flu-related deaths worldwide are higher than previously thought. The study suggests that...
Compounding pharmacies are pharmacies that create personalized medications by mixing ingredients based on a doctor's prescription in an effort to meet a person's needs. Though compounding pharmacies lost popularity in the 50s and 60s when mass drug manufacturing...
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