How to Store DNA Oligos: Best Practices for Longevity and Stability
Reliable storage practices not only extend the shelf life of oligos but also contribute to the accuracy and reproducibility of experimental results.
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Genetics & Genomics
Biotheranostics: Revolutionizing Cancer Treatment with Precision Medicine
The field of biotheranostics is rapidly evolving, with ongoing research focused on identifying new biomarkers, developing novel diagnostic tests, and discovering new targeted therapies.
Understanding NP_001786.2: A Key Protein in Human Biology
Understanding the function and importance of NP_001786.2 is essential for advancing research in sleep disorders, metabolic health, cardiovascular diseases, and cancer.
pCas-Guide: A Powerful Tool for CRISPR-Cas9 Genome Editing
CRISPR-Cas9 technology has revolutionized the field of genetic engineering by providing a precise, efficient, and flexible method for genome editing. One of the key advancements in this area is the development of pCas-Guide, a versatile tool that facilitates the...
The Need for Lab Experts in Coagulation, Complement, and Genetics
Machaon Diagnostics Founder and CEO Michael Ero joins us to discuss some of the challenges and successes of working with rare disease studies in this Ask the Expert exclusive.
The Differences Between Cell Therapy and Gene Therapy
Cell Therapy and Gene Therapy Research and Development Cell and gene therapy are similar fields of biomedical research aimed at treating genetic diseases and are often combined in treatment. Cell therapy was introduced in the 1940s during the first blood...
Immunogenicity of Biologics
The US Food and Drug Administration defines biologics as "a wide range of products such as vaccines, blood and blood components, allergenics, somatic cells, gene therapy, tissues, and recombinant therapeutic proteins...composed of sugars, proteins, or nucleic acids...
Residual DNA Testing: Understanding Host Cell DNA Analysis in Biopharmaceuticals
By detecting and quantifying trace amounts of host cell DNA, manufacturers can ensure the safety, quality, and compliance of their products.
Pharmacogenetics Testing | Precision Medicine Testing
Pharmacogenetics is a branch of science that studies how a person's genetics influence their response to pharmaceuticals (read an entry to pharmacogenetics, here). Adverse Drug Reactions (ADRs) are one of the biggest influences in the study of pharmacogenetics, as...
Proteomic Profile Techniques
Proteomics is a part of molecular biology that studies proteins. A proteome is a set of proteins that are either produced or modified by an organism and proteomics helps us understand things like the structure and function of the protein in an organism. The first...
Bacteria Whole Genome Sequencing (WGS) | Pulsed-Field Gel Electrophoresis (PFGE)
How PFGE and WGS are used to detect illness outbreaks? DNA fingerprinting is often performed on bacteria isolated from people who are sick by using techniques called pulsed-field gel electrophoresis (PFGE) and whole-genome sequencing (WGS). These techniques provide...
Liposome Research and Testing
Looking for liposome research? According to the US Food and Drug Administration (USFDA) Guidance Document entitled "Liposome Drug Products", a liposome is a microvesicle composed of a bilayer of lipid amphipathic molecules enclosing an aqueous compartment. It...
What is CRISPR? A Comprehensive Guide for Laboratory Professionals
CRISPR is said to be "an easy, cheap, and very precise way to edit the DNA of living cells."
Genotyping
Genotyping is a process used to obtain DNA information, specifically used to determine the genetic variants or differences an individual has. Common genotyping methods include restriction fragment length polymorphism identification of genomic DNA, polymerase chain...
Pharmacogenetics
Pharmacogenetics is the study of how genetic differences affect a person's response to medicine. Pharmacogenetics is often used interchangeably with pharmacogenomics. Pharmacogenetic research and testing determine a person's ability to metabolize medicines and...
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Editor's Choice
Electronic Device Testing: Ensuring Safety and Compliance for Tablets and Laptops in Schools
In today’s digital age, tablets and laptops have become essential tools in...
Chemical Safety Testing of School Supplies: Ensuring Crayons, Markers, and Glue Are Safe for Children
As children head back to school, parents, teachers, and caregivers focus on...
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