Contract testing laboratories now have a powerful new tool for advanced HLA typing with the release of Thermo Fisher Scientific’s One Lambda™ HybriType™ HLA Plus Typing Flex kit. This next-generation sequencing (NGS) solution uses a hybrid capture, probe-based assay to maximize read balance and reduce allele dropout—critical for ensuring accurate and reliable genotyping.
Tailored for flexibility, the HybriType kit supports Class I (4-field) and Class II (3-field) genotyping across multiple sample types, including whole blood and buccal swabs. With the ability to cover 18 loci—11 standard HLA loci plus 7 optional MHC loci and ABO blood group markers—contract labs can adjust the assay to fit diverse client requirements.
The streamlined protocol reduces total workflow time to under 5.5 hours, requiring less than 2.5 hours of hands-on work. When integrated with TypeStream™ Visual NGS Software, labs benefit from automated, accurate analysis, making it ideal for high-throughput environments that demand both speed and precision.
Key Benefits for Contract Testing Laboratories
- Customizable Testing Scope: Modular assay supports 18 loci including optional MHC and ABO markers.
- Rapid Turnaround: Sample-to-sequencing in less than 5.5 hours supports fast client reporting.
- Low Hands-On Time: Under 2.5 hours of technician input improves lab throughput.
- High Concordance: ≥99.8% genotyping accuracy reduces ambiguity in reporting.
- Multi-Sample Flexibility: Suitable for blood and buccal swab specimens.
This article has been sourced from a press release and may include content created or refined using AI tools and verified by our editorial team. The original press release was provided by Thermo Fisher Scientific.
