Genetics & Genomics

DNA Testing Software, FaSTR™ DNA v1.2, Enhanced

By Science Technology | Oct 16, 2024

Delivering comprehensive DNA analysis for complex forensic profiles

Screen shot of the DNA testing software FaSTR DNA

Genetic Methylation Test: A Laboratory Guide to Principles and Methods

By Trevor Henderson | Sep 26, 2024

There are several methods for analyzing DNA methylation, each with its advantages, limitations, and applications.

image illustrating the concept of genetic methylation. This image shows a DNA double helix with highlighted CpG sites, demonstrating the attachment of methyl groups (CH3) to cytosine bases. It visually captures the differences between methylated and unmethylated regions, making it an informative representation of the genetic methylation process.

How to Store DNA Oligos: Best Practices for Longevity and Stability

By Trevor Henderson | Aug 30, 2024

Reliable storage practices not only extend the shelf life of oligos but also contribute to the accuracy and reproducibility of experimental results.

an artful image showing a modern laboratory freezer with a background of stylized DNA oligo structures. This visual combines the elements of scientific precision and artistic representation, emphasizing the importance of proper storage in genetic research. The scene reflects a high-tech, organized research environment, with DNA samples and molecular structures highlighted in the design.

Biotheranostics: Revolutionizing Cancer Treatment with Precision Medicine

By Trevor Henderson | Aug 30, 2024

The field of biotheranostics is rapidly evolving, with ongoing research focused on identifying new biomarkers, developing novel diagnostic tests, and discovering new targeted therapies.

an illustrative image supporting the concept of biotheranostics in cancer treatment. It shows a futuristic lab environment, highlighting the advanced techniques involved in molecular diagnostics and precision medicine for personalized cancer care. The visual elements such as DNA strands, digital screens displaying genetic data, and a scientist analyzing samples emphasize the integration of technology and biology in modern cancer treatment.

Understanding NP_001786.2: A Key Protein in Human Biology

By Trevor Henderson | Aug 30, 2024

Understanding the function and importance of NP_001786.2 is essential for advancing research in sleep disorders, metabolic health, cardiovascular diseases, and cancer.

illustrative image supporting the article on NP_001786.2, showing the role of the BMAL1 protein in circadian rhythm regulation. The image includes molecular structures interacting with DNA strands, along with time-related imagery to represent the circadian cycle, all set in a modern laboratory environment. This visual highlights the connection between genetics, circadian biology, and ongoing research.

pCas-Guide: A Powerful Tool for CRISPR-Cas9 Genome Editing

By Trevor Henderson | Aug 30, 2024

CRISPR-Cas9 technology has revolutionized the field of genetic engineering by providing a precise, efficient, and flexible method for genome editing. One of the key advancements in this area is the development of pCas-Guide, a versatile tool that facilitates the...

an illustrative image that depicts the concept of pCas-Guide, showing a plasmid vector and elements of CRISPR-Cas9 genome editing, including DNA strands and the Cas9 protein. This image highlights the scientific and technological aspects of genetic engineering using pCas-Guide.

ASK THE LAB EXPECT: Machaon Diagnostics |The Need for Lab Experts in Coagulation, Complement, and Genetics

By Marnie Willman | Mar 27, 2024

Machaon Diagnostics Founder and CEO Michael Ero joins us to discuss some of the challenges and successes of working with rare disease studies in this Ask the Expert exclusive.

Image of DNA with red spot indication a point mutation

The Differences Between Cell Therapy and Gene Therapy: A Comprehensive Guide

By Pam Wertalik | Mar 7, 2023

Cell and gene therapy are similar fields of biomedical research aimed at treating genetic diseases and are often combined in treatment.

Immunogenicity Testing of Biologics: Ensuring Safety and Efficacy in Biopharmaceuticals

By Pam Wertalik | Mar 6, 2023

The rise of biologic therapies has revolutionized treatment options across various medical fields. However, one critical challenge remains: immunogenicity—the ability of biologic drugs to trigger immune responses in patients. Immunogenicity testing of biologics is...

Residual DNA Testing: Understanding Host Cell DNA Analysis in Biopharmaceuticals

By Trevor Henderson | Mar 4, 2023

By detecting and quantifying trace amounts of host cell DNA, manufacturers can ensure the safety, quality, and compliance of their products.

image of a modern laboratory, complete with advanced equipment and an artful representation of a DNA double helix in the background. The scene highlights the precision and innovation involved in DNA analysis and biopharmaceutical research

Pharmacogenetics Testing | Precision Medicine Testing

By Editorial Team | Mar 2, 2023

Pharmacogenetics is a branch of science that studies how a person's genetics influence their response to pharmaceuticals (read an entry to pharmacogenetics, here). Adverse Drug Reactions (ADRs) are one of the biggest influences in the study of pharmacogenetics, as...

Proteomic Profile Techniques

By Editorial Team | Feb 26, 2023

Proteomics is a part of molecular biology that studies proteins. A proteome is a set of proteins that are either produced or modified by an organism and proteomics helps us understand things like the structure and function of the protein in an organism. The first...

Bacteria Whole Genome Sequencing (WGS) | Pulsed-Field Gel Electrophoresis (PFGE)

By Editorial Team | Feb 25, 2023

How PFGE and WGS are used to detect illness outbreaks? DNA fingerprinting is often performed on bacteria isolated from people who are sick by using techniques called pulsed-field gel electrophoresis (PFGE) and whole-genome sequencing (WGS). These techniques provide...

Liposome Research and Testing

By Editorial Team | Feb 24, 2023

Looking for liposome research? According to the US Food and Drug Administration (USFDA) Guidance Document entitled "Liposome Drug Products", a liposome is a microvesicle composed of a bilayer of lipid amphipathic molecules enclosing an aqueous compartment. It...