About 20% of ovarian cancers are found at early stages yet when found early, 94% of patients live more than 5 years after their diagnosis.
Early detection of cancer is important in the treatment of disease. A blood test created by the Georgia Institute of Technology detects ovarian cancer with 90 percent accuracy. To read the article, visit here. According to the American Cancer Society, only about 20 percent of ovarian cancers are found at early stages yet when it is found early, 94 percent of patients live more than 5 years after their diagnosis.
Ovarian cancer is the 5th leading cause of death for women in the US and is often difficult to detect in early stages because many women are asymptomatic. In the test developed by the Georgia Institute of Technology, researchers studied blood serum compounds with differing molecular weights in order to establish a biomarker that is an effective tool to use in early-stage ovarian cancer screenings. Early-stage detection is essential as the survival rate is almost 90 percent when the disease is detected early.
Using a combination of techniques including liquid chromatography, mass spectrometry, and algorithms, the researchers were able to identify a number of women with early-stage ovarian cancer. These techniques also helped researchers identify 16 metabolite compounds used to differentiate between women with and without early-stage ovarian cancer with high accuracy. The study is a good indicator that combining algorithms with analytical chemistry techniques shows promise for diagnostic testing.
Previously, ovarian cancer was detected during a regular women’s health exam where a healthcare professional would feel the ovaries to determine size and shape, however, tumors on the ovaries are extremely difficult to feel. Transvaginal ultrasounds which use sound waves to look at the reproductive organs were another commonly used method of ovarian cancer screening, though this method could detect masses, it couldn’t determine whether or not they were cancerous.
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